The likes of Tom Brady, John Elway, Dan Marino, Y.A Tittle, Sonny Jurgensen, Drew Brees, Aaron Rodgers, and even Favre himself sent out their congratulations to Manning. The Broncos' record-breaker also found Wes Welker, Emmanuel Sanders in the end zone, and Thomas for another 40-yard score. Peyton Manning reached the milestone in his 246th regular season game, while Favre needed 302.
Thomas ended the game with 8 catches for 171 yards, and has 27 catches for 521 yards and 5 TD's over the last 3 games. The closest the 49ers would get is 21-10 after Colin Kaepernick's 4-yard TD to Stevie Johnson before the half. Kaepernick was sacked 6 times, twice by Von Miller and 3 times by DeMarcus Ware. With the loss, the 49ers fall to 4-3 on the year going in to a bye week, before hosting the St. Louis Rams November 2nd. The Broncos move to 5-1, with a short week coming up, hosting the San Diego Chargers Thursday night.