Clyde Edwards-Helaire. ran for 133 yards to lead LSU, who got six catches for 108 yards from Justin Jefferson, while Nick Brosette also found the end zone in the win. Jake Fromm struggled for the Bulldogs, throwing for 209 yards on 16-of-34 passing, including a touchdown and two interceptions. The quarterback admitted after the game that he was seeing formations from the Tigers that he had not seen while studying their games throughout the year.
Another ranked showdown came from the Pac-12, which also resulted in a top-10 team going down, as No. 7 Washington could not hold off No. 17 Oregon in overtime on the road. C.J. Verdell scored on a six-yard touchdown run in overtime, sending the Ducks to a 30-27 win over the Huskies. Verdell's game-winning score was his second of the game, as he ran for 111 yards on 29 carries.
Oregon earned their first win over Washington in three years, as it has been all Huskies each of the past two seasons in this conference rivalry. Washington snapped a 12-game losing streak against the Ducks two years ago with a 70-21 blowout in Oregon, before taking them down with ease, 38-3, at home last season. The loss is their second of the season, both of which came against ranked teams, including a season-opening loss to Auburn. Jake Browning threw for 243 yards and a touchdown in the loss, as they sit just a half-game ahead of Oregon in the Pac-12.
Elsewhere in the Top 10, the Iowa State Cyclones defended home field and handed the sixth-ranked West Virginia Mountaineers their first loss, 30-14. Brock Purdy threw for 254 yards and three touchdowns, while David Montgomery ran for 189 yards and a score on the night. The freshman Purdy helped Iowa State pull away in the fourth with 10 points, as the Cyclones improved to .500 overall and in conference play. ISU head coach Matt Campbell now has three wins over top six teams since October of 2017, and his team will be home next week against Texas Tech.
And in the Big Ten, the eighth-ranked Penn State Nittany Lions suffered their second home loss in the past three weeks, and Saturday's was a major upset. Brian Lewerke found Felton Davis for a 25-yard touchdown pass with 19 seconds left, giving Michigan State a 21-17 road win. Davis finished with eight catches for 100 yards and two touchdowns, as Penn State had a couple of unlucky moments cost them at home. That included Trace McSorely slipping on fourth down, a defender slipping to leave Davis wide open on his first touchdown catch, and Miles Sanders slipping inside the five, keeping the Nittany Lions out of the end zone. Sanders did run for 162 yards and a touchdown, but Penn State dropped a game under .500 in conference play.