Victor Martinez also went deep and drove in four two-out runs, while compiling three hits on the day. The Tigers knocked Masahiro Tanaka around after being outscored 21-5 in the first two games of the series. Andrew Romine hit his first home run of the year off the first major-league pitch from reliever Jose De Paula.
Anibal Sanchez got the win to run his record to 6-7, despite losing his 21 2/3 inning scoreless streak when Brian McCann went deep in the second inning. Sanchez shut down the Yankees' offense in seven innings of work to record his third straight win. He gave up seven hits and three runs, while handing New York just their second loss in 13 home games.
Martinez hit his first two home runs off of Tanaka, who gave up three home runs in a game for the first time in his career. The Tigers' right-fielder hit his last home run off of Danny Burawa in the sixth to give Detroit an 11-2 lead. He flied out to right in the eighth inning to end his day at the plate.
Tanaka gave up a career-high tying 10 hits and seven runs in five innings, as he fell to 2-2 since his return from the DL.
It was the first three-homer day for the Tigers since Miguel Cabrera did it at Texas on May 19th, 2013. Martinez is the first Tiger since Charlie Maxwell in 1959 to go deep three times against the Yankees.
Stephen Drew recorded his third multihomer game of the year for New York, as he hit two big flies to right field. His first was off of Sanchez in the seventh, and then he added another off of Joakim Soria in the ninth.
Detroit heads to Cleveland for a division showdown with the Indians beginning Monday, while the Yankees will host the Philadelphia Phillies in an interleague battle on Monday night.