Fejedelem was forced to be on the field at this time due to starting safety Shawn Williams getting ejected following a helmet-to-helmet hit to Luck. The backup entered the game with 25 tackles in his first two NFL seasons, as he finished with 10 tackles on Sunday and his first-career NFL score.
The win for the Bengals snaps their eight-game losing streak at Indianapolis, as they have now won four of their past five season openers. Dalton completed 21-of-28 passes for 243 yards, two touchdowns, and one interception, helping them overcome a six-point halftime deficit.
Luck, making his first regular season NFL start in 20 months, finished 39-of-53 for 319 yards and two touchdowns, as he proved that he is not afraid to throw the football. His interception came on his first throw of the season, but he did help the Colts get out to a 13-point lead in the first half.
Dalton did find A.J. Green for a 38-yard touchdown, while Joe Mixon added a score and totaled 149 yards on the day. The Bengals will have a short week and will host the Baltimore Ravens on Thursday night, while Luck's second start back will come on the road against the Washington Redskins.